Brg1 modulates enhancer activation in mesoderm lineage commitment
نویسندگان
چکیده
منابع مشابه
Brg1 modulates enhancer activation in mesoderm lineage commitment
The interplay between different levels of gene regulation in modulating developmental transcriptional programs, such as histone modifications and chromatin remodeling, is not well understood. Here, we show that the chromatin remodeling factor Brg1 is required for enhancer activation in mesoderm induction. In an embryonic stem cell-based directed differentiation assay, the absence of Brg1 result...
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متن کاملDev109496 1..13
The interplay between different levels of gene regulation in modulating developmental transcriptional programs, such as histonemodifications and chromatin remodeling, is not well understood. Here, we show that the chromatin remodeling factor Brg1 is required for enhancer activation in mesoderm induction. In an embryonic stem cell-based directed differentiation assay, the absence of Brg1 results...
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The interplay between different levels of gene regulation in modulating developmental transcriptional programs, such as histonemodifications and chromatin remodeling, is not well understood. Here, we show that the chromatin remodeling factor Brg1 is required for enhancer activation in mesoderm induction. In an embryonic stem cell-based directed differentiation assay, the absence of Brg1 results...
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ژورنال
عنوان ژورنال: Development
سال: 2015
ISSN: 1477-9129,0950-1991
DOI: 10.1242/dev.109496